A number of ongoing program in cancer research at Baylor College of Medicine have common areas of molecular biology, chemotherapy, virology and immunology. The application is a logical outgrowth of various efforts of the investigators who have common areas of interest and common goals that will utilize similar types of investigative tools in molecular biology and virology particularly. In addition, it is anticipated that clinically useful information will be derived from both basic science and clinical studies in chemotherapy and immunology.